Cargando…

Hydrocortisone-induced parkin prevents dopaminergic cell death via CREB pathway in Parkinson’s disease model

Dysfunctional parkin due to mutations or post-translational modifications contributes to dopaminergic neurodegeneration in Parkinson’s disease (PD). Overexpression of parkin provides protection against cellular stresses and prevents dopamine cell loss in several PD animal models. Here we performed a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ham, Sangwoo, Lee, Yun-Il, Jo, Minkyung, Kim, Hyojung, Kang, Hojin, Jo, Areum, Lee, Gum Hwa, Mo, Yun Jeong, Park, Sang Chul, Lee, Yun Song, Shin, Joo-Ho, Lee, Yunjong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428870/ https://www.ncbi.nlm.nih.gov/pubmed/28366931 http://dx.doi.org/10.1038/s41598-017-00614-w

Ejemplares similares

Activation of the ATF2/CREB-PGC-1α pathway by metformin leads to dopaminergic neuroprotection
por: Kang, Hojin, et al.
Publicado: (2017)

CRISPR-Cas9 Mediated Telomere Removal Leads to Mitochondrial Stress and Protein Aggregation
por: Kim, Hyojung, et al.
Publicado: (2017)

VPS35 regulates parkin substrate AIMP2 toxicity by facilitating lysosomal clearance of AIMP2
por: Yun, Seung Pil, et al.
Publicado: (2017)

Efficient Mitochondrial Genome Editing by CRISPR/Cas9
por: Jo, Areum, et al.
Publicado: (2015)

Estrogen receptor activation contributes to RNF146 expression and neuroprotection in Parkinson's disease models
por: Kim, Hyojung, et al.
Publicado: (2017)

Therapeutic Evaluation of Synthetic Peucedanocoumarin III in an Animal Model of Parkinson’s Disease
por: Ham, Sangwoo, et al.
Publicado: (2019)

Identification and evaluation of midbrain specific longevity-related genes in exceptionally long-lived but healthy mice
por: Kim, Hyojung, et al.
Publicado: (2023)

Deubiquitinase USP29 Governs MYBBP1A in the Brains of Parkinson’s Disease Patients
por: Jo, Areum, et al.
Publicado: (2019)

Phytochemical and Pharmacological Role of Liquiritigenin and Isoliquiritigenin From Radix Glycyrrhizae in Human Health and Disease Models
por: Ramalingam, Mahesh, et al.
Publicado: (2018)

Brain Endothelial P-Glycoprotein Level Is Reduced in Parkinson’s Disease via a Vitamin D Receptor-Dependent Pathway
por: Kim, Hyojung, et al.
Publicado: (2020)

Cell-Based Screen Using Amyloid Mimic β23 Expression Identifies Peucedanocoumarin III as a Novel Inhibitor of α-Synuclein and Huntingtin Aggregates
por: Ham, Sangwoo, et al.
Publicado: (2019)

TTC3 contributes to TGF-β(1)-induced epithelial−mesenchymal transition and myofibroblast differentiation, potentially through SMURF2 ubiquitylation and degradation
por: Kim, June-Hyung, et al.
Publicado: (2019)

Poly (ADP-ribose) in the pathogenesis of Parkinson's disease
por: Lee, Yunjong, et al.
Publicado: (2014)

Novel Nasal Epithelial Cell Markers of Parkinson’s Disease Identified Using Cells Treated with α-Synuclein Preformed Fibrils
por: Kim, Hyojung, et al.
Publicado: (2020)

Crosstalk of parkin and Ret in dopaminergic neurons
por: Kramer, Edgar R.
Publicado: (2015)

Quantitative analysis of nasal transcripts reveals potential biomarkers for Parkinson’s disease
por: Kim, Hyojung, et al.
Publicado: (2019)

Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation
por: Khang, Rin, et al.
Publicado: (2021)

Parthanatos Mediates AIMP2 Activated Age Dependent Dopaminergic Neuronal Loss
por: Lee, Yunjong, et al.
Publicado: (2013)

The c-Abl inhibitor, Nilotinib, protects dopaminergic neurons in a preclinical animal model of Parkinson's disease
por: Karuppagounder, Senthilkumar S., et al.
Publicado: (2014)

α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism
por: Yun, Seung Pil, et al.
Publicado: (2018)

Are PARKIN patients ideal candidates for dopaminergic cell replacement therapies?
por: Kunath, Tilo, et al.
Publicado: (2019)

Identification and Molecular Characterization of Parkin in Clonorchis sinensis
por: Bai, Xuelian, et al.
Publicado: (2015)

Genetic factors affecting dopaminergic deterioration during the premotor stage of Parkinson disease
por: Lee, Myung Jun, et al.
Publicado: (2021)

Sulfhydration mediates neuroprotective actions of parkin
por: Vandiver, M. Scott, et al.
Publicado: (2013)

Clinical Features Indicating Nigrostriatal Dopaminergic Degeneration in Drug-Induced Parkinsonism
por: Lee, Seung Ha, et al.
Publicado: (2017)

Molecular Aspects of Dopaminergic Neurodegeneration: Gene-Environment Interaction in Parkin Dysfunction
por: Ali, Syed F., et al.
Publicado: (2011)

Author Correction: Genetic factors affecting dopaminergic deterioration during the premotor stage of Parkinson disease
por: Lee, Myung Jun, et al.
Publicado: (2022)

Activation of ATM/Akt/CREB/eNOS Signaling Axis by Aphidicolin Increases NO Production and Vessel Relaxation in Endothelial Cells and Rat Aortas
por: Park, Jung-Hyun, et al.
Publicado: (2020)

Cell-Permeable Parkin Proteins Suppress Parkinson Disease-Associated Phenotypes in Cultured Cells and Animals
por: Duong, Tam, et al.
Publicado: (2014)

The neuroprotective and regenerative potential of parkin and GDNF/Ret signaling in the midbrain dopaminergic system
por: Kramer, Edgar R.
Publicado: (2015)

Oxidative switch drives mitophagy defects in dopaminergic parkin mutant patient neurons
por: Schwartzentruber, Aurelie, et al.
Publicado: (2020)

Salidroside Protects Dopaminergic Neurons by Enhancing PINK1/Parkin-Mediated Mitophagy
por: Li, Ruru, et al.
Publicado: (2019)

Particulate Matter Exacerbates the Death of Dopaminergic Neurons in Parkinson’s Disease through an Inflammatory Response
por: Choi, Dabin, et al.
Publicado: (2022)

Parkin beyond Parkinson’s Disease—A Functional Meaning of Parkin Downregulation in TDP-43 Proteinopathies
por: Gaweda-Walerych, Katarzyna, et al.
Publicado: (2021)

The Roles of PINK1 and Parkin in Parkinson's Disease
por: Jones, Rachel
Publicado: (2010)

Is PARKIN parkinsonism a cancer predisposition syndrome?
por: Schüle, Birgitt, et al.
Publicado: (2015)

Striatal Dopaminergic Loss and Dysphagia in Parkinson Disease
por: Kim, Ji Hwan, et al.
Publicado: (2023)

Determining Exposure Factors of Anti-Fogging, Dye, Disinfectant, Repellent, and Preservative Products in Korea
por: Lee, Daeyeop, et al.
Publicado: (2018)

Intracellular delivery of Parkin rescues neurons from accumulation of damaged mitochondria and pathological α-synuclein
por: Chung, Eunna, et al.
Publicado: (2020)

A Splice Intervention Therapy for Autosomal Recessive Juvenile Parkinson’s Disease Arising from Parkin Mutations
por: Li, Dunhui, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fdr4ho80cl18jsebo7pt5oq3df