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Hydrocortisone-induced parkin prevents dopaminergic cell death via CREB pathway in Parkinson’s disease model
Dysfunctional parkin due to mutations or post-translational modifications contributes to dopaminergic neurodegeneration in Parkinson’s disease (PD). Overexpression of parkin provides protection against cellular stresses and prevents dopamine cell loss in several PD animal models. Here we performed a...
Autores principales: | Ham, Sangwoo, Lee, Yun-Il, Jo, Minkyung, Kim, Hyojung, Kang, Hojin, Jo, Areum, Lee, Gum Hwa, Mo, Yun Jeong, Park, Sang Chul, Lee, Yun Song, Shin, Joo-Ho, Lee, Yunjong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428870/ https://www.ncbi.nlm.nih.gov/pubmed/28366931 http://dx.doi.org/10.1038/s41598-017-00614-w |
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