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High mobility group box 1 induces calcification of aortic valve interstitial cells via toll-like receptor 4

Chronic inflammation and the calcification of aortic valve interstitial cells (AVICs) are the primary etiologies of calcific aortic valve disease (CAVD). However, the underlying mechanism remains to be elucidated. The present study investigated the importance of high mobility group box 1 (HMGB1) via...

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Detalles Bibliográficos
Autores principales: Shen, Wenjun, Zhou, Jianqing, Wang, Chaoyang, Xu, Guangze, Wu, Ying, Hu, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428883/
https://www.ncbi.nlm.nih.gov/pubmed/28260034
http://dx.doi.org/10.3892/mmr.2017.6287