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Assessment of the quality of DNA from various formalin-fixed paraffin-embedded (FFPE) tissues and the use of this DNA for next-generation sequencing (NGS) with no artifactual mutation
Formalin-fixed, paraffin-embedded (FFPE) tissues used for pathological diagnosis are valuable for studying cancer genomics. In particular, laser-capture microdissection of target cells determined by histopathology combined with FFPE tissue section immunohistochemistry (IHC) enables precise analysis...
Autores principales: | Einaga, Naoki, Yoshida, Akio, Noda, Hiroko, Suemitsu, Masaaki, Nakayama, Yuki, Sakurada, Akihisa, Kawaji, Yoshiko, Yamaguchi, Hiromi, Sasaki, Yasushi, Tokino, Takashi, Esumi, Mariko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428915/ https://www.ncbi.nlm.nih.gov/pubmed/28498833 http://dx.doi.org/10.1371/journal.pone.0176280 |
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