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Notch ligands regulate the muscle stem-like state ex vivo but are not sufficient for retaining regenerative capacity
Myogenic stem cells are a promising avenue for the treatment of muscular disorders. Freshly isolated muscle stem cells have a remarkable engraftment ability in vivo, but their cell number is limited. Current conventional culture conditions do not allow muscle stem cells to expand in vitro with their...
Autores principales: | Sakai, Hiroshi, Fukuda, Sumiaki, Nakamura, Miki, Uezumi, Akiyoshi, Noguchi, Yu-taro, Sato, Takahiko, Morita, Mitsuhiro, Yamada, Harumoto, Tsuchida, Kunihiro, Tajbakhsh, Shahragim, Fukada, So-ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428926/ https://www.ncbi.nlm.nih.gov/pubmed/28498863 http://dx.doi.org/10.1371/journal.pone.0177516 |
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