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Three-dimensional system enabling the maintenance and directed differentiation of pluripotent stem cells under defined conditions

The development of in vitro models for the maintenance and differentiation of pluripotent stem cells (PSCs) is an active area of stem cell research. The strategies used so far are based mainly on two-dimensional (2D) cultures, in which cellular phenotypes are regulated by soluble factors. We show th...

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Detalles Bibliográficos
Autores principales: Zujur, Denise, Kanke, Kosuke, Lichtler, Alexander C., Hojo, Hironori, Chung, Ung-il, Ohba, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429032/
https://www.ncbi.nlm.nih.gov/pubmed/28508073
http://dx.doi.org/10.1126/sciadv.1602875

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