Hepatic effects of tartrazine (E 102) after systemic exposure are independent of oestrogen receptor interactions in the mouse

Tartrazine is a food colour that activates the transcriptional function of the human oestrogen receptor alpha in an in vitro cell model. Since oestrogens are cholestatic, we hypothesised tartrazine will cause periportal injury to the liver in vivo. To test this hypothesis, tartrazine was initially a...

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Detalles Bibliográficos
Autores principales: Meyer, Stephanie K., Probert, Philip M.E., Lakey, Anne F., Axon, Andrew R., Leitch, Alistair C., Williams, Faith M., Jowsey, Paul A., Blain, Peter G., Kass, George E.N., Wright, Matthew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429395/
https://www.ncbi.nlm.nih.gov/pubmed/28356238
http://dx.doi.org/10.1016/j.toxlet.2017.03.024

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