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Cerebellum: An explanation for dystonia?
Dystonia is a movement disorder that is characterized by involuntary muscle contractions, abnormal movements and postures, as well as by non-motor symptoms, and is due to abnormalities in different brain areas. In this article, we focus on the growing number of experimental studies aimed at explaini...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429509/ https://www.ncbi.nlm.nih.gov/pubmed/28515949 http://dx.doi.org/10.1186/s40673-017-0064-8 |
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author | Bologna, Matteo Berardelli, Alfredo |
author_facet | Bologna, Matteo Berardelli, Alfredo |
author_sort | Bologna, Matteo |
collection | PubMed |
description | Dystonia is a movement disorder that is characterized by involuntary muscle contractions, abnormal movements and postures, as well as by non-motor symptoms, and is due to abnormalities in different brain areas. In this article, we focus on the growing number of experimental studies aimed at explaining the pathophysiological role of the cerebellum in dystonia. Lastly, we highlight gaps in current knowledge and issues that future research studies should focus on as well as some of the potential applications of this research avenue. Clarifying the pathophysiological role of cerebellum in dystonia is an important concern given the increasing availability of invasive and non-invasive stimulation techniques and their potential therapeutic role in this condition. |
format | Online Article Text |
id | pubmed-5429509 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-54295092017-05-17 Cerebellum: An explanation for dystonia? Bologna, Matteo Berardelli, Alfredo Cerebellum Ataxias Review Dystonia is a movement disorder that is characterized by involuntary muscle contractions, abnormal movements and postures, as well as by non-motor symptoms, and is due to abnormalities in different brain areas. In this article, we focus on the growing number of experimental studies aimed at explaining the pathophysiological role of the cerebellum in dystonia. Lastly, we highlight gaps in current knowledge and issues that future research studies should focus on as well as some of the potential applications of this research avenue. Clarifying the pathophysiological role of cerebellum in dystonia is an important concern given the increasing availability of invasive and non-invasive stimulation techniques and their potential therapeutic role in this condition. BioMed Central 2017-05-12 /pmc/articles/PMC5429509/ /pubmed/28515949 http://dx.doi.org/10.1186/s40673-017-0064-8 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Bologna, Matteo Berardelli, Alfredo Cerebellum: An explanation for dystonia? |
title | Cerebellum: An explanation for dystonia? |
title_full | Cerebellum: An explanation for dystonia? |
title_fullStr | Cerebellum: An explanation for dystonia? |
title_full_unstemmed | Cerebellum: An explanation for dystonia? |
title_short | Cerebellum: An explanation for dystonia? |
title_sort | cerebellum: an explanation for dystonia? |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429509/ https://www.ncbi.nlm.nih.gov/pubmed/28515949 http://dx.doi.org/10.1186/s40673-017-0064-8 |
work_keys_str_mv | AT bolognamatteo cerebellumanexplanationfordystonia AT berardellialfredo cerebellumanexplanationfordystonia |