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Cerebellum: An explanation for dystonia?

Dystonia is a movement disorder that is characterized by involuntary muscle contractions, abnormal movements and postures, as well as by non-motor symptoms, and is due to abnormalities in different brain areas. In this article, we focus on the growing number of experimental studies aimed at explaini...

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Detalles Bibliográficos
Autores principales: Bologna, Matteo, Berardelli, Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429509/
https://www.ncbi.nlm.nih.gov/pubmed/28515949
http://dx.doi.org/10.1186/s40673-017-0064-8
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author Bologna, Matteo
Berardelli, Alfredo
author_facet Bologna, Matteo
Berardelli, Alfredo
author_sort Bologna, Matteo
collection PubMed
description Dystonia is a movement disorder that is characterized by involuntary muscle contractions, abnormal movements and postures, as well as by non-motor symptoms, and is due to abnormalities in different brain areas. In this article, we focus on the growing number of experimental studies aimed at explaining the pathophysiological role of the cerebellum in dystonia. Lastly, we highlight gaps in current knowledge and issues that future research studies should focus on as well as some of the potential applications of this research avenue. Clarifying the pathophysiological role of cerebellum in dystonia is an important concern given the increasing availability of invasive and non-invasive stimulation techniques and their potential therapeutic role in this condition.
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spelling pubmed-54295092017-05-17 Cerebellum: An explanation for dystonia? Bologna, Matteo Berardelli, Alfredo Cerebellum Ataxias Review Dystonia is a movement disorder that is characterized by involuntary muscle contractions, abnormal movements and postures, as well as by non-motor symptoms, and is due to abnormalities in different brain areas. In this article, we focus on the growing number of experimental studies aimed at explaining the pathophysiological role of the cerebellum in dystonia. Lastly, we highlight gaps in current knowledge and issues that future research studies should focus on as well as some of the potential applications of this research avenue. Clarifying the pathophysiological role of cerebellum in dystonia is an important concern given the increasing availability of invasive and non-invasive stimulation techniques and their potential therapeutic role in this condition. BioMed Central 2017-05-12 /pmc/articles/PMC5429509/ /pubmed/28515949 http://dx.doi.org/10.1186/s40673-017-0064-8 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Bologna, Matteo
Berardelli, Alfredo
Cerebellum: An explanation for dystonia?
title Cerebellum: An explanation for dystonia?
title_full Cerebellum: An explanation for dystonia?
title_fullStr Cerebellum: An explanation for dystonia?
title_full_unstemmed Cerebellum: An explanation for dystonia?
title_short Cerebellum: An explanation for dystonia?
title_sort cerebellum: an explanation for dystonia?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429509/
https://www.ncbi.nlm.nih.gov/pubmed/28515949
http://dx.doi.org/10.1186/s40673-017-0064-8
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