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ERK signaling is required for VEGF-A/VEGFR2-induced differentiation of porcine adipose-derived mesenchymal stem cells into endothelial cells

BACKGROUND: Cell-based therapy that can rejuvenate the endothelium with stimulated adipose-derived mesenchymal stem cells (AMSCs) is a promising therapeutic strategy for the re-endothelialization of denuded arteries at the stenting site. Previously, we have shown that silencing of MMP-2 and MMP-14 i...

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Detalles Bibliográficos
Autores principales: Almalki, Sami G., Agrawal, Devendra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429549/
https://www.ncbi.nlm.nih.gov/pubmed/28499402
http://dx.doi.org/10.1186/s13287-017-0568-4