Cargando…

The role of BRCA1-IRIS in the development and progression of triple negative breast cancers in Egypt: possible link to disease early lesion

BACKGROUND: Breast cancer is the most globally diagnosed female cancer, with the triple negative breast cancer (TNBC) being the most aggressive subtype of the disease. In this study we aimed at comparing the effect of BRCA1-IRIS overexpression on the clinico-pathological characteristics in breast ca...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bogan, Danielle, Meile, Lucio, El Bastawisy, Ahmed, Yousef, Hend F., Zekri, Abdel-Rahman N., Bahnassy, Abeer A., ElShamy, Wael M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429567/ https://www.ncbi.nlm.nih.gov/pubmed/28499366 http://dx.doi.org/10.1186/s12885-017-3283-8

Ejemplares similares

BRCA1-IRIS overexpression promotes and maintains the tumor initiating phenotype: implications for triple negative breast cancer early lesions
por: Sinha, Abhilasha, et al.
Publicado: (2016)

A niche that triggers aggressiveness within BRCA1-IRIS overexpressing triple negative tumors is supported by reciprocal interactions with the microenvironment
por: Ryan, Daniel, et al.
Publicado: (2017)

Correction: A niche that triggers aggressiveness within BRCA1-IRIS overexpressing triple negative tumors is supported by reciprocal interactions with the microenvironment
por: Ryan, Daniel, et al.
Publicado: (2017)

BRCA1-IRIS inactivation overcomes paclitaxel resistance in triple negative breast cancers
por: Blanchard, Zannel, et al.
Publicado: (2015)

The role of BRCA1-IRIS in ovarian cancer formation, drug resistance and progression
por: ElShamy, Wael M.
Publicado: (2016)

BRCA1/p220 loss triggers BRCA1-IRIS overexpression via mRNA stabilization in breast cancer cells
por: Shimizu, Yoshiko, et al.
Publicado: (2012)

The pro- and anti-tumor roles of mesenchymal stem cells toward BRCA1-IRIS-overexpressing TNBC cells
por: Ryan, Daniel, et al.
Publicado: (2019)

The role of CD68+ macrophage in classical Hodgkin lymphoma patients from Egypt
por: Mohamed, Osama, et al.
Publicado: (2020)

BRCA1-IRIS Overexpression Promotes Formation of Aggressive Breast Cancers
por: Shimizu, Yoshiko, et al.
Publicado: (2012)

Transforming growth factor-β, insulin-like growth factor I/insulin-like growth factor I receptor and vascular endothelial growth factor-A: Prognostic and predictive markers in triple-negative and non-triple-negative breast cancer
por: BAHHNASSY, ABEER, et al.
Publicado: (2015)

Targeting AXL and RAGE to prevent geminin overexpression-induced triple-negative breast cancer metastasis
por: Ryan, Daniel, et al.
Publicado: (2019)

Investigation of chromosomal aberrations in Egyptian hepatocellular carcinoma patients by fluorescence in situ hybridization
por: Aly, Magdy S., et al.
Publicado: (2010)

Cancer in Africa: Is It a Genetic or Environmental Health Problem?
por: Bahnassy, Abeer A., et al.
Publicado: (2020)

Prognostic Impact of BRCA1 and BRCA2 Mutations on Long-Term Survival Outcomes in Egyptian Female Breast Cancer Patients
por: AbdelHamid, Sherihan, et al.
Publicado: (2021)

Consensus siRNA for inhibition of HCV genotype-4 replication
por: Zekri, Abdel Rahman N, et al.
Publicado: (2009)

The possible role of cell cycle regulators in multistep process of HPV-associated cervical carcinoma
por: Bahnassy, Abeer A, et al.
Publicado: (2007)

Dynamic interplay between CXCL levels in chronic Hepatitis C patients treated by Interferon
por: Zekri, Abdel-Rahman N, et al.
Publicado: (2013)

Aggressiveness Niche: Can It Be the Foster Ground for Cancer Metastasis Precursors?
por: ElShamy, Wael M., et al.
Publicado: (2016)

Geminin overexpression-dependent recruitment and crosstalk with mesenchymal stem cells enhance aggressiveness in triple negative breast cancers
por: Ananthula, Suryatheja, et al.
Publicado: (2016)

Epigenetic inactivation of DNA repair genes as promising prognostic and predictive biomarkers in urothelial bladder carcinoma patients
por: Mohanad, Marwa, et al.
Publicado: (2022)

Cyclin A and cyclin D1 as significant prognostic markers in colorectal cancer patients
por: Bahnassy, Abeer A, et al.
Publicado: (2004)

Genetic profiling of different phenotypic subsets of breast cancer stem cells (BCSCs) in breast cancer patients
por: Zekri, Abdel-Rahman N., et al.
Publicado: (2022)

Genomic characterization of SARS-CoV-2 in Egypt
por: Zekri, Abdel-Rahman N., et al.
Publicado: (2020)

Assessment of the Circulating Tumor Cells and Microsatellite Instability in Colorectal Cancer Patients: Prognostic and Diagnostic Value
por: Alsayed, Aya, et al.
Publicado: (2021)

The possible role of Dickkopf-1, Golgi protein- 73 and Midkine as predictors of hepatocarcinogenesis: a review and an Egyptian study
por: N Zekri, Abdel-Rahman, et al.
Publicado: (2020)

Geminin overexpression prevents the completion of topoisomerase IIα chromosome decatenation, leading to aneuploidy in human mammary epithelial cells
por: Gardner, Lauren, et al.
Publicado: (2011)

Geminin Overexpression Promotes Imatinib Sensitive Breast Cancer: A Novel Treatment Approach for Aggressive Breast Cancers, Including a Subset of Triple Negative
por: Blanchard, Zannel, et al.
Publicado: (2014)

Characterization of the SARS-CoV-2 genomes in Egypt in first and second waves of infection
por: Zekri, Abdel-Rahman N., et al.
Publicado: (2021)

Characterization of chronic HCV infection-induced apoptosis
por: Zekri, Abdel-Rahman N, et al.
Publicado: (2011)

Genetic distance and heterogenecity between quasispecies is a critical predictor to IFN response in Egyptian patients with HCV genotype-4
por: Zekri, Abdel Rahman N, et al.
Publicado: (2007)

A model of the BRCA1/BRCA2 network
por: Pujana, MA, et al.
Publicado: (2005)

Assessment of health-related quality of life in patients receiving stem cell therapy for end-stage liver disease: an Egyptian study
por: Salama, Hosny, et al.
Publicado: (2012)

Serum levels of soluble Fas, soluble tumor necrosis factor-receptor II, interleukin-2 receptor and interleukin-8 as early predictors of hepatocellular carcinoma in Egyptian patients with hepatitis C virus genotype-4
por: Zekri, Abdel-Rahman N, et al.
Publicado: (2010)

Clinical significance of altered nm23-H1, EGFR, RB and p53 expression in bilharzial bladder cancer
por: Khaled, Hussein M, et al.
Publicado: (2009)

Role of relevant immune-modulators and cytokines in hepatocellular carcinoma and premalignant hepatic lesions
por: Zekri, Abdel-Rahman N, et al.
Publicado: (2018)

Outcome of Rhabdomyosarcoma in First Year of Life: Children's Cancer Hospital 57357 Egypt
por: El Nadi, Enas, et al.
Publicado: (2013)

New insight into HCV E1/E2 region of genotype 4a
por: Hussein, Nehal, et al.
Publicado: (2014)

Personal protective equipment used by obstetricians and obstetric nurses during the COVID-19 pandemic in Mansoura, Egypt
por: Khashaba, Eman, et al.
Publicado: (2022)

Seroprevalence and risk factors of tropical theileriosis in smallholder asymptomatic large ruminants in Egypt
por: El Damaty, Hend M., et al.
Publicado: (2022)

Simultaneous Detection of Mycobacterium tuberculosis and Atypical Mycobacteria by DNA-Microarray in Egypt
por: Gaballah, Ahmed, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ap9brgddeaf7vqo6ubmupkcni8