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Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells

BACKGROUND: Polysialic acid (polySia) is a carbohydrate modification of the neural cell adhesion molecule (NCAM), which is implicated in neural differentiation and plays an important role in tumor development and metastasis. Polysialylation of NCAM is mediated by two Golgi-resident polysialyltransfe...

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Detalles Bibliográficos
Autores principales:	Somplatzki, Stefan, Mühlenhoff, Martina, Kröger, Andrea, Gerardy-Schahn, Rita, Böldicke, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429572/ https://www.ncbi.nlm.nih.gov/pubmed/28499450 http://dx.doi.org/10.1186/s12896-017-0360-7

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