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Sodium fluoride induces nephrotoxicity via oxidative stress-regulated mitochondrial SIRT3 signaling pathway

Accumulation of mitochondrial reactive oxygen species (mROS) has been implicated in the pathogenesis of fluorosis. As the main mitochondrial deacetylase, SIRT3 is closely associated with oxidative stress. To investigate the role of SIRT3 in response to sodium fluoride (NaF)-induced nephrotoxicity. O...

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Detalles Bibliográficos
Autores principales:	Song, Chao, Fu, Beibei, Zhang, Jingcheng, Zhao, Jiamin, Yuan, Mengke, Peng, Wei, Zhang, Yong, Wu, Haibo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429606/ https://www.ncbi.nlm.nih.gov/pubmed/28386112 http://dx.doi.org/10.1038/s41598-017-00796-3

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