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Structural Insight into the Specific DNA Template Binding to DnaG primase in Bacteria

Bacterial primase initiates the repeated synthesis of short RNA primers that are extended by DNA polymerase to synthesize Okazaki fragments on the lagging strand at replication forks. It remains unclear how the enzyme recognizes specific initiation sites. In this study, the DnaG primase from Bacillu...

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Detalles Bibliográficos
Autores principales: Zhou, Yingqin, Luo, Hao, Liu, Zhongchuan, Yang, Mu, Pang, Xiaoyun, Sun, Fei, Wang, Ganggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429622/
https://www.ncbi.nlm.nih.gov/pubmed/28386108
http://dx.doi.org/10.1038/s41598-017-00767-8