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The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation
The COP9 signalosome (CSN) is an evolutionary conserved multiprotein complex that regulates many aspects of plant development by controlling the activity of CULLIN-RING E3 ubiquitin ligases (CRLs). CRLs ubiquitinate and target for proteasomal degradation a vast number of specific substrate proteins...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429640/ https://www.ncbi.nlm.nih.gov/pubmed/28377589 http://dx.doi.org/10.1038/s41598-017-00744-1 |
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author | Pacurar, Daniel Ioan Pacurar, Monica Lacramioara Lakehal, Abdellah Pacurar, Andrea Mariana Ranjan, Alok Bellini, Catherine |
author_facet | Pacurar, Daniel Ioan Pacurar, Monica Lacramioara Lakehal, Abdellah Pacurar, Andrea Mariana Ranjan, Alok Bellini, Catherine |
author_sort | Pacurar, Daniel Ioan |
collection | PubMed |
description | The COP9 signalosome (CSN) is an evolutionary conserved multiprotein complex that regulates many aspects of plant development by controlling the activity of CULLIN-RING E3 ubiquitin ligases (CRLs). CRLs ubiquitinate and target for proteasomal degradation a vast number of specific substrate proteins involved in many developmental and physiological processes, including light and hormone signaling and cell division. As a consequence of CSN pleiotropic function, complete loss of CSN activity results in seedling lethality. Therefore, a detailed analysis of CSN physiological functions in adult Arabidopsis plants has been hampered by the early seedling lethality of csn null mutants. Here we report the identification and characterization of a viable allele of the Arabidopsis COP9 signalosome subunit 4 (CSN4). The allele, designated csn4-2035, suppresses the adventitious root (AR) phenotype of the Arabidopsis superroot2-1 mutant, potentially by altering its auxin signaling. Furthermore, we show that although the csn4-2035 mutation affects primary and lateral root (LR) formation in the 2035 suppressor mutant, CSN4 and other subunits of the COP9 complex seem to differentially control AR and LR development. |
format | Online Article Text |
id | pubmed-5429640 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-54296402017-05-15 The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation Pacurar, Daniel Ioan Pacurar, Monica Lacramioara Lakehal, Abdellah Pacurar, Andrea Mariana Ranjan, Alok Bellini, Catherine Sci Rep Article The COP9 signalosome (CSN) is an evolutionary conserved multiprotein complex that regulates many aspects of plant development by controlling the activity of CULLIN-RING E3 ubiquitin ligases (CRLs). CRLs ubiquitinate and target for proteasomal degradation a vast number of specific substrate proteins involved in many developmental and physiological processes, including light and hormone signaling and cell division. As a consequence of CSN pleiotropic function, complete loss of CSN activity results in seedling lethality. Therefore, a detailed analysis of CSN physiological functions in adult Arabidopsis plants has been hampered by the early seedling lethality of csn null mutants. Here we report the identification and characterization of a viable allele of the Arabidopsis COP9 signalosome subunit 4 (CSN4). The allele, designated csn4-2035, suppresses the adventitious root (AR) phenotype of the Arabidopsis superroot2-1 mutant, potentially by altering its auxin signaling. Furthermore, we show that although the csn4-2035 mutation affects primary and lateral root (LR) formation in the 2035 suppressor mutant, CSN4 and other subunits of the COP9 complex seem to differentially control AR and LR development. Nature Publishing Group UK 2017-04-04 /pmc/articles/PMC5429640/ /pubmed/28377589 http://dx.doi.org/10.1038/s41598-017-00744-1 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Pacurar, Daniel Ioan Pacurar, Monica Lacramioara Lakehal, Abdellah Pacurar, Andrea Mariana Ranjan, Alok Bellini, Catherine The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation |
title | The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation |
title_full | The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation |
title_fullStr | The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation |
title_full_unstemmed | The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation |
title_short | The Arabidopsis Cop9 signalosome subunit 4 (CSN4) is involved in adventitious root formation |
title_sort | arabidopsis cop9 signalosome subunit 4 (csn4) is involved in adventitious root formation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429640/ https://www.ncbi.nlm.nih.gov/pubmed/28377589 http://dx.doi.org/10.1038/s41598-017-00744-1 |
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