Toll-like receptor 7 deficiency protects apolipoprotein E-deficient mice from diet-induced atherosclerosis

Toll-like receptor 7 (TLR7) mediates autoantigen and viral RNA-induced cytokine production. Increased TLR7 expression in human atherosclerotic lesions suggests its involvement in atherogenesis. Here we demonstrated TLR7 expression in macrophages, smooth muscle cells (SMCs), and endothelial cells fro...

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Detalles Bibliográficos
Autores principales: Liu, Cong-Lin, Santos, Marcela M., Fernandes, Cleverson, Liao, Mengyang, Iamarene, Karine, Zhang, Jin-Ying, Sukhova, Galina K., Shi, Guo-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429799/
https://www.ncbi.nlm.nih.gov/pubmed/28405010
http://dx.doi.org/10.1038/s41598-017-00977-0

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