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Global analysis of glycoproteins identifies markers of endotoxin tolerant monocytes and GPR84 as a modulator of TNFα expression
Exposure of human monocytes to lipopolysaccharide (LPS) induces a temporary insensitivity to subsequent LPS challenges, a cellular state called endotoxin tolerance. In this study, we investigated the LPS-induced global glycoprotein expression changes of tolerant human monocytes and THP-1 cells to id...
Autores principales: | Müller, Mario M., Lehmann, Roland, Klassert, Tilman E., Reifenstein, Stella, Conrad, Theresia, Moore, Christoph, Kuhn, Anna, Behnert, Andrea, Guthke, Reinhard, Driesch, Dominik, Slevogt, Hortense |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429802/ https://www.ncbi.nlm.nih.gov/pubmed/28404994 http://dx.doi.org/10.1038/s41598-017-00828-y |
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