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The role of the SWI/SNF chromatin remodeling complex in maintaining the stemness of glioma initiating cells
Glioma initiating cells (GICs) are thought to contribute to therapeutic resistance and tumor recurrence in glioblastoma, a lethal primary brain tumor in adults. Although the stem-like properties of GICs, such as self-renewal and tumorigenicity, are epigenetically regulated, the role of a major chrom...
Autores principales: | Hiramatsu, Hiroaki, Kobayashi, Kazuyoshi, Kobayashi, Kyousuke, Haraguchi, Takeshi, Ino, Yasushi, Todo, Tomoki, Iba, Hideo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429847/ https://www.ncbi.nlm.nih.gov/pubmed/28420882 http://dx.doi.org/10.1038/s41598-017-00982-3 |
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