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Therapeutic targeting using tumor specific peptides inhibits long non-coding RNA HOTAIR activity in ovarian and breast cancer

Long non-coding RNAs (lncRNAs) play key roles in human diseases, including cancer. Functional studies of the lncRNA HOTAIR (HOX transcript antisense RNA) provide compelling evidence for therapeutic targeting of HOTAIR in cancer, but targeting lncRNAs in vivo has proven to be difficult. In the curren...

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Detalles Bibliográficos
Autores principales:	Özeş, Ali R., Wang, Yinu, Zong, Xingyue, Fang, Fang, Pilrose, Jay, Nephew, Kenneth P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429858/ https://www.ncbi.nlm.nih.gov/pubmed/28420874 http://dx.doi.org/10.1038/s41598-017-00966-3

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