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Additive Intraocular Pressure-Lowering Effects of Ripasudil with Glaucoma Therapeutic Agents in Rabbits and Monkeys
Ripasudil hydrochloride hydrate (K-115), a specific Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor, is developed for the treatment of glaucoma and ocular hypertension. Topical administration of ripasudil decreases intraocular pressure (IOP) by increasing conventional outflow t...
Autores principales: | Kaneko, Yoshio, Ohta, Masayuki, Isobe, Tomoyuki, Nakamura, Yuto, Mizuno, Ken |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5429944/ https://www.ncbi.nlm.nih.gov/pubmed/28540083 http://dx.doi.org/10.1155/2017/7079645 |
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