Cargando…
The Transcription Factor ZNF683/HOBIT Regulates Human NK-Cell Development
We identified ZNF683/HOBIT as the most highly upregulated transcription factor gene during ex vivo differentiation of human CD34(+) cord blood progenitor cells to CD56(+) natural killer (NK) cells. ZNF683/HOBIT mRNA was preferentially expressed in NK cells compared to other human peripheral blood ly...
Autores principales: | Post, Mirte, Cuapio, Angelica, Osl, Markus, Lehmann, Dorit, Resch, Ulrike, Davies, David M., Bilban, Martin, Schlechta, Bernhard, Eppel, Wolfgang, Nathwani, Amit, Stoiber, Dagmar, Spanholtz, Jan, Casanova, Emilio, Hofer, Erhard |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430038/ https://www.ncbi.nlm.nih.gov/pubmed/28555134 http://dx.doi.org/10.3389/fimmu.2017.00535 |
Ejemplares similares
-
IL-12 Directs Further Maturation of Ex Vivo Differentiated NK Cells with Improved Therapeutic Potential
por: Lehmann, Dorit, et al.
Publicado: (2014) -
Cancer-specific tissue-resident memory T-cells express ZNF683 in colorectal cancer
por: Kitakaze, Masatoshi, et al.
Publicado: (2023) -
Maintenance therapy with histamine plus IL-2 induces a striking expansion of two CD56(bright) NK cell subpopulations in patients with acute myeloid leukemia and supports their activation
por: Cuapio, Angélica, et al.
Publicado: (2016) -
The Transcription Factor Hobit Identifies Human Cytotoxic CD4(+) T Cells
por: Oja, Anna E., et al.
Publicado: (2017) -
Single‐cell transcriptome profiling reveals the key role of ZNF683 in natural killer cell exhaustion in multiple myeloma
por: Li, Xin, et al.
Publicado: (2022)