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Rapid‐eye‐movement sleep‐predominant central sleep apnea relieved by positive airway pressure: a case report
Central Sleep Apnea (CSA) is characterized by intermittent apneas and hypopneas during sleep that result from absent central respiratory drive. CSA occurs almost exclusively during non‐rapid‐eye‐movement (NREM) sleep due to enhanced neuronal ventilatory drive during REM sleep that makes central apne...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430122/ https://www.ncbi.nlm.nih.gov/pubmed/28483860 http://dx.doi.org/10.14814/phy2.13254 |
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author | Jouett, Noah P. Smith, Michael L. Watenpaugh, Donald E. Siddiqui, Maryam Ahmad, Maleeha Siddiqui, Farrukh |
author_facet | Jouett, Noah P. Smith, Michael L. Watenpaugh, Donald E. Siddiqui, Maryam Ahmad, Maleeha Siddiqui, Farrukh |
author_sort | Jouett, Noah P. |
collection | PubMed |
description | Central Sleep Apnea (CSA) is characterized by intermittent apneas and hypopneas during sleep that result from absent central respiratory drive. CSA occurs almost exclusively during non‐rapid‐eye‐movement (NREM) sleep due to enhanced neuronal ventilatory drive during REM sleep that makes central apneas highly unlikely to form. A 45‐year‐old obese African American female presented with co‐existing Obstructive Sleep Apnea (OSA) and CSA, not in the form of mixed or complex sleep apnea. Peculiarly, her CSA occurred only during rapid‐eye‐movement (REM) sleep, which is exceedingly rare. The patient's CSA was resolved when appropriate positive airway pressure (PAP) was prescribed. Our patient remains stable and has reported significant benefit from PAP usage. We offer possible neuro‐physiological mechanisms herein, including enhanced loop gain and/or malfunction or malformation of the pre‐Botzinger nucleus or other neurological process, that could explain the unique findings of this case. |
format | Online Article Text |
id | pubmed-5430122 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-54301222017-05-17 Rapid‐eye‐movement sleep‐predominant central sleep apnea relieved by positive airway pressure: a case report Jouett, Noah P. Smith, Michael L. Watenpaugh, Donald E. Siddiqui, Maryam Ahmad, Maleeha Siddiqui, Farrukh Physiol Rep Case Reports Central Sleep Apnea (CSA) is characterized by intermittent apneas and hypopneas during sleep that result from absent central respiratory drive. CSA occurs almost exclusively during non‐rapid‐eye‐movement (NREM) sleep due to enhanced neuronal ventilatory drive during REM sleep that makes central apneas highly unlikely to form. A 45‐year‐old obese African American female presented with co‐existing Obstructive Sleep Apnea (OSA) and CSA, not in the form of mixed or complex sleep apnea. Peculiarly, her CSA occurred only during rapid‐eye‐movement (REM) sleep, which is exceedingly rare. The patient's CSA was resolved when appropriate positive airway pressure (PAP) was prescribed. Our patient remains stable and has reported significant benefit from PAP usage. We offer possible neuro‐physiological mechanisms herein, including enhanced loop gain and/or malfunction or malformation of the pre‐Botzinger nucleus or other neurological process, that could explain the unique findings of this case. John Wiley and Sons Inc. 2017-05-08 /pmc/articles/PMC5430122/ /pubmed/28483860 http://dx.doi.org/10.14814/phy2.13254 Text en © 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Reports Jouett, Noah P. Smith, Michael L. Watenpaugh, Donald E. Siddiqui, Maryam Ahmad, Maleeha Siddiqui, Farrukh Rapid‐eye‐movement sleep‐predominant central sleep apnea relieved by positive airway pressure: a case report |
title | Rapid‐eye‐movement sleep‐predominant central sleep apnea relieved by positive airway pressure: a case report |
title_full | Rapid‐eye‐movement sleep‐predominant central sleep apnea relieved by positive airway pressure: a case report |
title_fullStr | Rapid‐eye‐movement sleep‐predominant central sleep apnea relieved by positive airway pressure: a case report |
title_full_unstemmed | Rapid‐eye‐movement sleep‐predominant central sleep apnea relieved by positive airway pressure: a case report |
title_short | Rapid‐eye‐movement sleep‐predominant central sleep apnea relieved by positive airway pressure: a case report |
title_sort | rapid‐eye‐movement sleep‐predominant central sleep apnea relieved by positive airway pressure: a case report |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430122/ https://www.ncbi.nlm.nih.gov/pubmed/28483860 http://dx.doi.org/10.14814/phy2.13254 |
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