Changes in Frequency and Activation Status of Major CD4(+) T-Cell Subsets after Initiation of Immunosuppressive Therapy in a Patient with New Diagnosis Childhood-Onset Systemic Lupus Erythematosus

BACKGROUND: Several studies suggest that defects of regulatory T-cells (Tregs) and impaired cellular immunity are secondary to an imbalance between auto-aggressive T-cells and Tregs in lupus patients. Discrepancies in Tregs and effector T-cells (Teff) in active lupus patients are shown to be restore...

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Detalles Bibliográficos
Autores principales: Singla, Saimun, Wenderfer, Scott E., Muscal, Eyal, Sagcal-Gironella, Anna Carmela P., Orange, Jordan S., Makedonas, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430328/
https://www.ncbi.nlm.nih.gov/pubmed/28555177
http://dx.doi.org/10.3389/fped.2017.00104

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