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Comparative analysis among three Taiwan-specific Gentiana species and Chinese medicinal plant Gentiana scabra

BACKGROUND: The root of Gentiana scabra is commonly known as Longdan in Chinese herbal medicines and has been used in the treatment of inflammation, anorexia, indigestion and gastric infections for over 2000 years. High market demand had made G. scabra (GS) plants not to be the only source of Longda...

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Autores principales: Huang, Shih-Hung, Chen, Emily hin-Fun, Wu, Chin-Tung, Kuo, Chao-Lin, Tsay, Hsin-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430382/
https://www.ncbi.nlm.nih.gov/pubmed/28510889
http://dx.doi.org/10.1186/1999-3110-54-54
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author Huang, Shih-Hung
Chen, Emily hin-Fun
Wu, Chin-Tung
Kuo, Chao-Lin
Tsay, Hsin-Sheng
author_facet Huang, Shih-Hung
Chen, Emily hin-Fun
Wu, Chin-Tung
Kuo, Chao-Lin
Tsay, Hsin-Sheng
author_sort Huang, Shih-Hung
collection PubMed
description BACKGROUND: The root of Gentiana scabra is commonly known as Longdan in Chinese herbal medicines and has been used in the treatment of inflammation, anorexia, indigestion and gastric infections for over 2000 years. High market demand had made G. scabra (GS) plants not to be the only source of Longdan in China, other Gentiana spp., G. triflora, G. manshurica and G. rigescens, were also recognized as Longdan in China now. RESULTS: In this study, we identified three Taiwan-specific Gentiana spp., G. davidii var. formosana (GDF) and G. arisanensis (GA) and G. scabrida var. punctulata (GSP) that are phylogenetically different from GS (main source of Longdan). However, the active compounds of Longdan, gentiopicroside and swertiamari, were found in GSP and GDF showed higher antioxidant ability and free radical scavenging activities than Chinese Longdan. This discovery might explore the medicinal potential of GDF. Meanwhile, another Taiwan-specific Gentiana spp., GSP, was found to have the strongest antioxidant ability and free radical scavenging activities which might suggest a possible use of GSP as a source of natural antioxidant agents for industrial purpose. CONCLUSIONS: The finding of this study indicated that ITS analysis can be used to identify Taiwan-specific Gentiana spp. Also the Taiwan-specific Gentiana spp. which has strongest antioxidant and free radical scavenging activities among others could be a better choice for industrial purpose. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1999-3110-54-54) contains supplementary material, which is available to authorized users.
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spelling pubmed-54303822017-05-30 Comparative analysis among three Taiwan-specific Gentiana species and Chinese medicinal plant Gentiana scabra Huang, Shih-Hung Chen, Emily hin-Fun Wu, Chin-Tung Kuo, Chao-Lin Tsay, Hsin-Sheng Bot Stud Research BACKGROUND: The root of Gentiana scabra is commonly known as Longdan in Chinese herbal medicines and has been used in the treatment of inflammation, anorexia, indigestion and gastric infections for over 2000 years. High market demand had made G. scabra (GS) plants not to be the only source of Longdan in China, other Gentiana spp., G. triflora, G. manshurica and G. rigescens, were also recognized as Longdan in China now. RESULTS: In this study, we identified three Taiwan-specific Gentiana spp., G. davidii var. formosana (GDF) and G. arisanensis (GA) and G. scabrida var. punctulata (GSP) that are phylogenetically different from GS (main source of Longdan). However, the active compounds of Longdan, gentiopicroside and swertiamari, were found in GSP and GDF showed higher antioxidant ability and free radical scavenging activities than Chinese Longdan. This discovery might explore the medicinal potential of GDF. Meanwhile, another Taiwan-specific Gentiana spp., GSP, was found to have the strongest antioxidant ability and free radical scavenging activities which might suggest a possible use of GSP as a source of natural antioxidant agents for industrial purpose. CONCLUSIONS: The finding of this study indicated that ITS analysis can be used to identify Taiwan-specific Gentiana spp. Also the Taiwan-specific Gentiana spp. which has strongest antioxidant and free radical scavenging activities among others could be a better choice for industrial purpose. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/1999-3110-54-54) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2013-11-05 /pmc/articles/PMC5430382/ /pubmed/28510889 http://dx.doi.org/10.1186/1999-3110-54-54 Text en © Huang et al.; licensee Springer. 2013 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Huang, Shih-Hung
Chen, Emily hin-Fun
Wu, Chin-Tung
Kuo, Chao-Lin
Tsay, Hsin-Sheng
Comparative analysis among three Taiwan-specific Gentiana species and Chinese medicinal plant Gentiana scabra
title Comparative analysis among three Taiwan-specific Gentiana species and Chinese medicinal plant Gentiana scabra
title_full Comparative analysis among three Taiwan-specific Gentiana species and Chinese medicinal plant Gentiana scabra
title_fullStr Comparative analysis among three Taiwan-specific Gentiana species and Chinese medicinal plant Gentiana scabra
title_full_unstemmed Comparative analysis among three Taiwan-specific Gentiana species and Chinese medicinal plant Gentiana scabra
title_short Comparative analysis among three Taiwan-specific Gentiana species and Chinese medicinal plant Gentiana scabra
title_sort comparative analysis among three taiwan-specific gentiana species and chinese medicinal plant gentiana scabra
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430382/
https://www.ncbi.nlm.nih.gov/pubmed/28510889
http://dx.doi.org/10.1186/1999-3110-54-54
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