Neuroglobin Can Prevent or Reverse Glaucomatous Progression in DBA/2J Mice

Mitochondrial dysfunction is responsible for hereditary optic neuropathies. We wished to determine whether preserving mitochondrial bioenergetics could prevent optic neuropathy in a reliable model of glaucoma. DBA/2J mice exhibit elevated intraocular pressure, progressive degeneration of their retin...

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Detalles Bibliográficos
Autores principales: Cwerman-Thibault, Hélène, Lechauve, Christophe, Augustin, Sébastien, Roussel, Delphine, Reboussin, Élodie, Mohammad, Ammara, Degardin-Chicaud, Julie, Simonutti, Manuel, Liang, Hong, Brignole-Baudouin, Françoise, Maron, Anne, Debeir, Thomas, Corral-Debrinski, Marisol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430497/
https://www.ncbi.nlm.nih.gov/pubmed/28540323
http://dx.doi.org/10.1016/j.omtm.2017.04.008

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