Temperature-dependent folding allows stable dimerization of secretory and virus-associated E proteins of Dengue and Zika viruses in mammalian cells

Dengue and Zika are two of the most important human viral pathogens worldwide. In both cases, the envelope glycoprotein E is the main target of the antibody response. Recently, new complex quaternary epitopes were identified which are the consequence of the arrangement of the antiparallel E dimers o...

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Detalles Bibliográficos
Autores principales: Slon Campos, J. L., Marchese, S., Rana, J., Mossenta, M., Poggianella, M., Bestagno, M., Burrone, O. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430527/
https://www.ncbi.nlm.nih.gov/pubmed/28424472
http://dx.doi.org/10.1038/s41598-017-01097-5

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