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Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia
Mitochondria use oxygen as the final acceptor of the respiratory chain, but its incomplete reduction can also produce reactive oxygen species (ROS), especially superoxide. Acute hypoxia produces a superoxide burst in different cell types, but the triggering mechanism is still unknown. Herein, we sho...
Autores principales: | Hernansanz-Agustín, Pablo, Ramos, Elena, Navarro, Elisa, Parada, Esther, Sánchez-López, Nuria, Peláez-Aguado, Laura, Cabrera-García, J. Daniel, Tello, Daniel, Buendia, Izaskun, Marina, Anabel, Egea, Javier, López, Manuela G., Bogdanova, Anna, Martínez-Ruiz, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430576/ https://www.ncbi.nlm.nih.gov/pubmed/28511347 http://dx.doi.org/10.1016/j.redox.2017.04.025 |
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