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Endogenous Two-Photon Excited Fluorescence Imaging Characterizes Neuron and Astrocyte Metabolic Responses to Manganese Toxicity

As neurodegenerative conditions are increasingly linked to mitochondrial dysfunction, methods for studying brain cell metabolism at high spatial resolution are needed to elucidate neurodegeneration mechanisms. Two-photon excited fluorescence (TPEF) imaging is a non-destructive, high-resolution techn...

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Detalles Bibliográficos
Autores principales: Stuntz, Emily, Gong, Yusi, Sood, Disha, Liaudanskaya, Volha, Pouli, Dimitra, Quinn, Kyle P., Alonzo, Carlo, Liu, Zhiyi, Kaplan, David L., Georgakoudi, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430620/
https://www.ncbi.nlm.nih.gov/pubmed/28432298
http://dx.doi.org/10.1038/s41598-017-01015-9