Dysregulation of Blimp1 transcriptional repressor unleashes p130Cas/ErbB2 breast cancer invasion

ErbB2 overexpression is detected in approximately 20% of breast cancers and is correlated with poor survival. It was previously shown that the adaptor protein p130Cas/BCAR1 is a crucial mediator of ErbB2 transformation and that its overexpression confers invasive properties to ErbB2-positive human m...

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Detalles Bibliográficos
Autores principales: Sciortino, Marianna, Camacho-Leal, Maria del Pilar, Orso, Francesca, Grassi, Elena, Costamagna, Andrea, Provero, Paolo, Tam, Wayne, Turco, Emilia, Defilippi, Paola, Taverna, Daniela, Cabodi, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430666/
https://www.ncbi.nlm.nih.gov/pubmed/28442738
http://dx.doi.org/10.1038/s41598-017-01332-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430666/
https://www.ncbi.nlm.nih.gov/pubmed/28442738
http://dx.doi.org/10.1038/s41598-017-01332-z

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