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Dysregulation of Blimp1 transcriptional repressor unleashes p130Cas/ErbB2 breast cancer invasion
ErbB2 overexpression is detected in approximately 20% of breast cancers and is correlated with poor survival. It was previously shown that the adaptor protein p130Cas/BCAR1 is a crucial mediator of ErbB2 transformation and that its overexpression confers invasive properties to ErbB2-positive human m...
Autores principales: | Sciortino, Marianna, Camacho-Leal, Maria del Pilar, Orso, Francesca, Grassi, Elena, Costamagna, Andrea, Provero, Paolo, Tam, Wayne, Turco, Emilia, Defilippi, Paola, Taverna, Daniela, Cabodi, Sara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430666/ https://www.ncbi.nlm.nih.gov/pubmed/28442738 http://dx.doi.org/10.1038/s41598-017-01332-z |
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