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Monitoring global protein thiol-oxidation and protein S-mycothiolation in Mycobacterium smegmatis under hypochlorite stress
Mycothiol (MSH) is the major low molecular weight (LMW) thiol in Actinomycetes. Here, we used shotgun proteomics, OxICAT and RNA-seq transcriptomics to analyse protein S-mycothiolation, reversible thiol-oxidations and their impact on gene expression in Mycobacterium smegmatis under hypochlorite stre...
Autores principales: | Hillion, Melanie, Bernhardt, Jörg, Busche, Tobias, Rossius, Martina, Maaß, Sandra, Becher, Dörte, Rawat, Mamta, Wirtz, Markus, Hell, Rüdiger, Rückert, Christian, Kalinowski, Jörn, Antelmann, Haike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430705/ https://www.ncbi.nlm.nih.gov/pubmed/28446771 http://dx.doi.org/10.1038/s41598-017-01179-4 |
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