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SLC10A4 regulates IgE-mediated mast cell degranulation in vitro and mast cell-mediated reactions in vivo

Mast cells act as sensors in innate immunity and as effector cells in adaptive immune reactions. Here we demonstrate that SLC10A4, also referred to as the vesicular aminergic-associated transporter, VAAT, modifies mast cell degranulation. Strikingly, Slc10a4 (−/−) bone marrow-derived mast cells (BMM...

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Detalles Bibliográficos
Autores principales:	Pettersson, Hanna, Zarnegar, Behdad, Westin, Annika, Persson, Viktor, Peuckert, Christiane, Jonsson, Jörgen, Hallgren, Jenny, Kullander, Klas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430724/ https://www.ncbi.nlm.nih.gov/pubmed/28439090 http://dx.doi.org/10.1038/s41598-017-01121-8

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