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Primate embryogenesis predicts the hallmarks of human naïve pluripotency

Naïve pluripotent mouse embryonic stem cells (ESCs) resemble the preimplantation epiblast and efficiently contribute to chimaeras. Primate ESCs correspond to the postimplantation embryo and fail to resume development in chimaeric assays. Recent data suggest that human ESCs can be ‘reset’ to an earli...

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Detalles Bibliográficos
Autores principales:	Boroviak, Thorsten, Nichols, Jennifer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2017
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430762/ https://www.ncbi.nlm.nih.gov/pubmed/28096211 http://dx.doi.org/10.1242/dev.145177

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