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Inhibition of protein kinases by anticancer DNA intercalator, 4-butylaminopyrimido[4′,5′:4,5]thieno(2,3-b)quinoline

Targeting protein kinases (PKs) has been a promising strategy in treating cancer, as PKs are key regulators of cell survival and proliferation. Here in this study, we studied the ability of pyrimido[4′,5′:4,5]thieno(2,3-b)quinolines (PTQ) to inhibit different PKs by performing computational docking...

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Detalles Bibliográficos
Autores principales: Rohit Kumar, HeggoduG., Kumar, Chethan S., Kiran Kumar, Hulihalli N., Advi Rao, Gopal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430831/
https://www.ncbi.nlm.nih.gov/pubmed/28540166
http://dx.doi.org/10.1016/j.apsb.2017.01.001