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3D Microfluidic model for evaluating immunotherapy efficacy by tracking dendritic cell behaviour toward tumor cells

Immunotherapy efficacy relies on the crosstalk within the tumor microenvironment between cancer and dendritic cells (DCs) resulting in the induction of a potent and effective antitumor response. DCs have the specific role of recognizing cancer cells, taking up tumor antigens (Ags) and then migrating...

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Detalles Bibliográficos
Autores principales: Parlato, Stefania, De Ninno, Adele, Molfetta, Rosa, Toschi, Elena, Salerno, Debora, Mencattini, Arianna, Romagnoli, Giulia, Fragale, Alessandra, Roccazzello, Lorenzo, Buoncervello, Maria, Canini, Irene, Bentivegna, Enrico, Falchi, Mario, Bertani, Francesca Romana, Gerardino, Annamaria, Martinelli, Eugenio, Natale, Corrado, Paolini, Rossella, Businaro, Luca, Gabriele, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430848/
https://www.ncbi.nlm.nih.gov/pubmed/28439087
http://dx.doi.org/10.1038/s41598-017-01013-x