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3D Microfluidic model for evaluating immunotherapy efficacy by tracking dendritic cell behaviour toward tumor cells
Immunotherapy efficacy relies on the crosstalk within the tumor microenvironment between cancer and dendritic cells (DCs) resulting in the induction of a potent and effective antitumor response. DCs have the specific role of recognizing cancer cells, taking up tumor antigens (Ags) and then migrating...
Autores principales: | Parlato, Stefania, De Ninno, Adele, Molfetta, Rosa, Toschi, Elena, Salerno, Debora, Mencattini, Arianna, Romagnoli, Giulia, Fragale, Alessandra, Roccazzello, Lorenzo, Buoncervello, Maria, Canini, Irene, Bentivegna, Enrico, Falchi, Mario, Bertani, Francesca Romana, Gerardino, Annamaria, Martinelli, Eugenio, Natale, Corrado, Paolini, Rossella, Businaro, Luca, Gabriele, Lucia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430848/ https://www.ncbi.nlm.nih.gov/pubmed/28439087 http://dx.doi.org/10.1038/s41598-017-01013-x |
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