Xanthine oxidase inhibition by febuxostat attenuates stress-induced hyperuricemia, glucose dysmetabolism, and prothrombotic state in mice

Chronic stress is closely linked to the metabolic syndrome, diabetes, hyperuricemia and thromboembolism, but the mechanisms remain elusive. We reported recently that stress targets visceral adipose tissue (VAT), inducing lipolysis, low-grade inflammation with production of inflammatory adipokines, m...

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Detalles Bibliográficos
Autores principales: Yisireyili, Maimaiti, Hayashi, Motoharu, Wu, Hongxian, Uchida, Yasuhiro, Yamamoto, Koji, Kikuchi, Ryosuke, Shoaib Hamrah, Mohammad, Nakayama, Takayuki, Wu Cheng, Xian, Matsushita, Tadashi, Nakamura, Shigeo, Niwa, Toshimitsu, Murohara, Toyoaki, Takeshita, Kyosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430858/
https://www.ncbi.nlm.nih.gov/pubmed/28455534
http://dx.doi.org/10.1038/s41598-017-01366-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5430858/
https://www.ncbi.nlm.nih.gov/pubmed/28455534
http://dx.doi.org/10.1038/s41598-017-01366-3

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