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High Fat Diet-Induced Hepatic 18-Carbon Fatty Acids Accumulation Up-Regulates CYP2A5/CYP2A6 via NF-E2-Related Factor 2

To investigate the role of hepatic 18-carbon fatty acids (FA) accumulation in regulating CYP2A5/2A6 and the significance of Nrf2 in the process during hepatocytes steatosis, Nrf2-null, and wild type mice fed with high-fat diet (HFD), and Nrf2 silenced or over expressed HepG2 cells administered with...

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Detalles Bibliográficos
Autores principales:	Wang, Xing-he, Cui, Xiao-xu, Sun, Xiao-qi, Wang, Xing-hui, Li, Xiao-chong, Qi, Yue, Li, Wei, Han, Mei-yu, Muhammad, Ishfaq, Zhang, Xiu-ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431014/ https://www.ncbi.nlm.nih.gov/pubmed/28555106 http://dx.doi.org/10.3389/fphar.2017.00233

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