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P(II) Protein-Derived FRET Sensors for Quantification and Live-Cell Imaging of 2-Oxoglutarate

The citric acid cycle intermediate 2-oxoglutarate (2-OG, a.k.a. alpha-ketoglutarate) links the carbon and nitrogen metabolic pathways and can provide information on the metabolic status of cells. In recent years, it has become exceedingly clear that 2-OG also acts as a master regulator of diverse bi...

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Detalles Bibliográficos
Autores principales: Lüddecke, Jan, Francois, Liliana, Spät, Philipp, Watzer, Björn, Chilczuk, Tomasz, Poschet, Gernot, Hell, Rüdiger, Radlwimmer, Bernhard, Forchhammer, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431102/
https://www.ncbi.nlm.nih.gov/pubmed/28469248
http://dx.doi.org/10.1038/s41598-017-01440-w