Functional organization of protein determinants of meiotic DNA break hotspots

During Schizosaccharomyces pombe meiotic prophase, homologous chromosomes are co-aligned by linear elements (LinEs) analogous to the axial elements of the synaptonemal complex (SC) in other organisms. LinE proteins also promote the formation of meiotic DNA double-strand breaks (DSBs), the precursors...

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Detalles Bibliográficos
Autores principales: Ma, Lijuan, Fowler, Kyle R., Martín-Castellanos, Cristina, Smith, Gerald R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431104/
https://www.ncbi.nlm.nih.gov/pubmed/28469148
http://dx.doi.org/10.1038/s41598-017-00742-3

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