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Mitochondria-targeted antioxidants as highly effective antibiotics

Mitochondria-targeted antioxidants are known to alleviate mitochondrial oxidative damage that is associated with a variety of diseases. Here, we showed that SkQ1, a decyltriphenyl phosphonium cation conjugated to a quinone moiety, exhibited strong antibacterial activity towards Gram-positive Bacillu...

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Detalles Bibliográficos
Autores principales: Nazarov, Pavel A., Osterman, Ilya A., Tokarchuk, Artem V., Karakozova, Marina V., Korshunova, Galina A., Lyamzaev, Konstantin G., Skulachev, Maxim V., Kotova, Elena A., Skulachev, Vladimir P., Antonenko, Yuri N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431119/
https://www.ncbi.nlm.nih.gov/pubmed/28469140
http://dx.doi.org/10.1038/s41598-017-00802-8

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