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Impaired renal function and dysbiosis of gut microbiota contribute to increased trimethylamine-N-oxide in chronic kidney disease patients

Chronic kidney disease (CKD) patients have an increased risk of cardiovascular diseases (CVDs). The present study aimed to investigate the gut microbiota and blood trimethylamine-N-oxide concentration (TMAO) in Chinese CKD patients and explore the underlying explanations through the animal experimen...

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Detalles Bibliográficos
Autores principales: Xu, Kai-Yu, Xia, Geng-Hong, Lu, Jun-Qi, Chen, Mu-Xuan, Zhen, Xin, Wang, Shan, You, Chao, Nie, Jing, Zhou, Hong-Wei, Yin, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431124/
https://www.ncbi.nlm.nih.gov/pubmed/28469156
http://dx.doi.org/10.1038/s41598-017-01387-y