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Simultaneous Quantification of Amino Metabolites in Multiple Metabolic Pathways Using Ultra-High Performance Liquid Chromatography with Tandem-mass Spectrometry

Metabolites containing amino groups cover multiple pathways and play important roles in redox homeostasis and biosyntheses of proteins, nucleotides and neurotransmitters. Here, we report a new method for simultaneous quantification of 124 such metabolites. This is achieved by derivatization-assisted...

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Detalles Bibliográficos
Autores principales: Wang, Jin, Zhou, Lihong, Lei, Hehua, Hao, Fuhua, Liu, Xin, Wang, Yulan, Tang, Huiru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431165/
https://www.ncbi.nlm.nih.gov/pubmed/28469184
http://dx.doi.org/10.1038/s41598-017-01435-7