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The Regulatory T-cell Transcription Factor Foxp3 Protects against Crescentic Glomerulonephritis
Regulatory T cells (Tregs) have been shown to play a protective role in glomerulonephritis (GN) and Foxp3 is a master transcription factor in Treg development. In this study, we examined the functional role and mechanisms of Foxp3 in a mouse model of accelerated anti-glomerular basement membrane (an...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431186/ https://www.ncbi.nlm.nih.gov/pubmed/28469165 http://dx.doi.org/10.1038/s41598-017-01515-8 |