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Role of differentially expressed microRNA-139-5p in the regulation of phenotypic internal anal sphincter smooth muscle tone

The present study focused on the role of microRNA-139-5p (miRNA-139-5p) in the regulation of basal tone in internal anal sphincter (IAS). Applying genome-wide miRNA microarrays on the phenotypically distinct smooth muscle cells (SMCs) within the rat anorectrum, we identified miRNA-139-5p as differen...

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Detalles Bibliográficos
Autores principales: Singh, Jagmohan, Mohanty, Ipsita, Addya, Sankar, Phillips, Benjamin, Mee Yong, Hwan, An, Steven S., Penn, Raymond B., Rattan, Satish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431208/
https://www.ncbi.nlm.nih.gov/pubmed/28469189
http://dx.doi.org/10.1038/s41598-017-01550-5