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Generation of mutation hotspots in ageing bacterial colonies

How do ageing bacterial colonies generate adaptive mutants? Over a period of two months, we isolated on ageing colonies outgrowing mutants able to use a new carbon source, and sequenced their genomes. This allowed us to uncover exquisite details on the molecular mechanism behind their adaptation: mo...

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Detalles Bibliográficos
Autores principales: Sekowska, Agnieszka, Wendel, Sofie, Fischer, Emil C., Nørholm, Morten H. H., Danchin, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431349/
https://www.ncbi.nlm.nih.gov/pubmed/28442761
http://dx.doi.org/10.1038/s41598-016-0005-4

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