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Generation of mutation hotspots in ageing bacterial colonies
How do ageing bacterial colonies generate adaptive mutants? Over a period of two months, we isolated on ageing colonies outgrowing mutants able to use a new carbon source, and sequenced their genomes. This allowed us to uncover exquisite details on the molecular mechanism behind their adaptation: mo...
Autores principales: | Sekowska, Agnieszka, Wendel, Sofie, Fischer, Emil C., Nørholm, Morten H. H., Danchin, Antoine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431349/ https://www.ncbi.nlm.nih.gov/pubmed/28442761 http://dx.doi.org/10.1038/s41598-016-0005-4 |
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