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Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease

Krabbe disease (KD) is a neurodegenerative disorder caused by the lack of β- galactosylceramidase enzymatic activity and by widespread accumulation of the cytotoxic galactosyl-sphingosine in neuronal, myelinating and endothelial cells. Despite the wide use of Twitcher mice as experimental model for...

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Detalles Bibliográficos
Autores principales:	Cappello, Valentina, Marchetti, Laura, Parlanti, Paola, Landi, Silvia, Tonazzini, Ilaria, Cecchini, Marco, Piazza, Vincenzo, Gemmi, Mauro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431369/ https://www.ncbi.nlm.nih.gov/pubmed/28442746 http://dx.doi.org/10.1038/s41598-016-0001-8

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