DNA Methyltransferase1 (DNMT1) Isoform3 methylates mitochondrial genome and modulates its biology

Here we demonstrate localization of the isoform3 of DNA Methyltransferase1 (DNMT1) enzyme to mitochondria, instead of isoform1 as reported earlier. The fused DNMT1-isoform1, reported earlier to localize in mitochondria, surprisingly showed its exclusive presence inside the nucleus after its ectopic...

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Detalles Bibliográficos
Autores principales: Saini, Sunil Kumar, Mangalhara, Kailash Chandra, Prakasam, Gopinath, Bamezai, R. N. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431478/
https://www.ncbi.nlm.nih.gov/pubmed/28484249
http://dx.doi.org/10.1038/s41598-017-01743-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431478/
https://www.ncbi.nlm.nih.gov/pubmed/28484249
http://dx.doi.org/10.1038/s41598-017-01743-y

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