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DNA Methyltransferase1 (DNMT1) Isoform3 methylates mitochondrial genome and modulates its biology
Here we demonstrate localization of the isoform3 of DNA Methyltransferase1 (DNMT1) enzyme to mitochondria, instead of isoform1 as reported earlier. The fused DNMT1-isoform1, reported earlier to localize in mitochondria, surprisingly showed its exclusive presence inside the nucleus after its ectopic...
Autores principales: | Saini, Sunil Kumar, Mangalhara, Kailash Chandra, Prakasam, Gopinath, Bamezai, R. N. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431478/ https://www.ncbi.nlm.nih.gov/pubmed/28484249 http://dx.doi.org/10.1038/s41598-017-01743-y |
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