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CRISPR/Cas9-mediated mutation of tyrosinase (Tyr) 3′ UTR induce graying in rabbit

The 3′ untranslated regions (UTRs), located at the end of mRNA molecules, are believed to play a role in RNA replication and/or protein translation. Mutations in the tyrosinase (Tyr) gene are known to cause recessive albinism in humans and other species. In this study, to test whether the CRISPR/Cas...

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Detalles Bibliográficos
Autores principales:	Song, Yuning, Xu, Yuxin, Deng, Jichao, Chen, Mao, Lu, Yi, Wang, Yong, Yao, Haobin, Zhou, Lina, Liu, Zhiquan, Lai, Liangxue, Li, Zhanjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431497/ https://www.ncbi.nlm.nih.gov/pubmed/28484254 http://dx.doi.org/10.1038/s41598-017-01727-y

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