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Intestinal Epithelial Cell-Specific Deletion of PLD2 Alleviates DSS-Induced Colitis by Regulating Occludin
Ulcerative colitis is a multi-factorial disease involving a dysregulated immune response. Disruptions to the intestinal epithelial barrier and translocation of bacteria, resulting in inflammation, are common in colitis. The mechanisms underlying epithelial barrier dysfunction or regulation of tight...
Autores principales: | Chelakkot, Chaithanya, Ghim, Jaewang, Rajasekaran, Nirmal, Choi, Jong-Sun, Kim, Jung-Hwan, Jang, Myoung Ho, Shin, Young Kee, Suh, Pann-Ghill, Ryu, Sung Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431506/ https://www.ncbi.nlm.nih.gov/pubmed/28484281 http://dx.doi.org/10.1038/s41598-017-01797-y |
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