Paternal spatial training enhances offspring’s cognitive performance and synaptic plasticity in wild-type but not improve memory deficit in Alzheimer’s mice

Recent studies suggest that spatial training can maintain associative memory capacity in Tg2576 mice, but it is not known whether the beneficial effects can be inherited from the trained fathers to their offspring. Here, we exposed male wild-type and male 3XTg Alzheimer disease (AD) mice (3-m old) r...

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Detalles Bibliográficos
Autores principales: Zhang, Shujuan, Li, Xiaoguang, Wang, Zhouyi, Liu, Yanchao, Gao, Yuan, Tan, Lu, Liu, Enjie, Zhou, Qiuzhi, Xu, Cheng, Wang, Xin, Liu, Gongping, Chen, Haote, Wang, Jian-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5431522/
https://www.ncbi.nlm.nih.gov/pubmed/28484240
http://dx.doi.org/10.1038/s41598-017-01811-3

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